Henry Ford Center for Precision Diagnostics Organ Specific Panels and Fusion Gene Panels Single Genes BRAF KRAS NRAS Microsatellite Instability + IHC Reflex- MLH1 Methylation KIT PDGFRA Fusion Solid Tumor Panel- 50 Genes Breast HER-2 protein, IHC Lung 6-Gene Panel BRAF, ERBB2, EGFR, KRAS, MET, NRAS Reflex FISH for- ALK and ROS1 rearrangements Fusion Genes ALK, ROS1, RET, MET, NTRK1, NTRK2, NTRK3 Melanoma 6-Gene Panel BRAF, NRAS, KIT, PDGFRA, GNA11, GNAQ KIT alone Brain EGFR vIII IDH1 IDH2 MGMT Methylation 1p19qLOH Colorectal & Endometrial 3-Gene Panel BRAF, KRAS, NRAS Gastro- intestinal Gastrointestinal Stromal Tumor Panel Fusion Panels Fusion Sarcoma Panel- 26 Genes More detailed information and requisition forms available at www.HenryFord.com/HFCPD PD-L1 (clone 22C3) IHC PD-L1 (clone 28-2) IHC HER-2 Dual ISH HER-2 gene amplification, FISH